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Geplaatst: 17-03-2020 09:48:13

Peptides can be synthesized with known post-translational modifications andor deliberately introduced with protease-resistant peptide bonds to regulate their processing independent of tissue-specific proteolysis and to stabilize these compounds in vivo. Peptides can be used for many therapeutic medicinal purposes, as well as in high-end cosmetic products - like the Dermaxime range of anti-aging skin care cosmetics. Synthetic peptides have been developed, which contain active ingredients that can rival the results of laser treatments or surgical face lifts and there are continuous new developments and advances made in this field. The list of peptides as potential drugs is huge and hundreds are well advanced on the path of drug development processes; space does not permit discussion of them all. It is beyond the scope of this article to focus on older peptide therapies such as luteinizing-hormone-releasing hormone, growth hormone Brad Guzan USA Jersey , arginine vasopressin or the very interesting peptide, cyclosporin. We will instead highlight some exciting new areas of research as well as recent developments in the use of more established peptide therapies. Insulin was the first peptide to be isolated and administered therapeutically, and is still the most commonly prescribed peptide, having been used for over half a century. We have yet to find a chemical mimic; however Brad Evans USA Jersey , there is still ongoing research into novel analogues and methods of administration. Manipulation of the insulin molecule has allowed the development of shorter-acting insulins, such as Lispro insulin. This is rapidly absorbed, readily dissociates into insulin monomers, and produces plasma levels that more closely mimic the normal postprandial insulin profile. Thus Brad Davis USA Jersey , Lispro can be injected immediately prior to a meal, unlike conventional short-acting insulins that should be injected half an hour earlier. A recent development is the use of non-injectable forms of insulin. Daily injections up to four times per day, is a major source of distress in the diabetic population, for example children or the elderly. It comes as no surprise that inhaled Bobby Wood USA Jersey , intranasal, buccal, rectal and sub-lingual preparations of insulin have all been investigated. Precise insulin dosage is critical for `brittle' type 1 diabetics. However, for some Bill Hamid USA Jersey , e.g. people with type 2 diabetes that have significant residual endogenous insulin secretion, less accurate forms of administration may be adequate. Recent results shows that inhaled insulin provided glycemic control equivalent to the subcutaneous route, whilst allowing insulin to be taken immediately before a meal. Thus, the future seems to be more hopeful for the `multiply-punctured diabetic'.

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BB Cream Provides an Organic Alternative to Makeup and Skincare

by gauravgvr89 · December 2 Aron Johannsson USA Jersey , 2019

According to the findings of a report by Grand View Research, Inc., the BB cream market stood at USD 2.11 billion in 2018 and is expected to attain a CAGR of 14.4% over the forecast period (2019 to 2025). Rising demand for high quality skincare products among young consumers is anticipated to propel the demand for Blemish Balm (BB) creams in the forthcoming period. Increase in number of working population comprising of youth and rising number of double income families is expected to further drive the demand for BB creams. Major cosmetic companies are inclined to introduce natural, herbal Alejandro Bedoya USA Jersey , and organic products which is likely to have a positive impact and create new opportunities in future.

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